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Levamisole HCL

Synonyms:

* Levasole, Tetramisole hydrochloride, Levomysol hydrochloride,

* 14769-73-4, * 24593-45-1, * 39170-95-1, * 74191-78-9,

* (-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole monohydrochloride,

* Ascaridil, * C07906, * Citarin L, * Decaris, * Dekaris, * DRG-0245,

* EINECS 240-654-6, * Ergamisol, * Ergamisol (TN),

* Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI),

* Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-,

* Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-,

* KW 2LE-T, * KW-2-LE-T,

* L-(-)-2,3,5,6-Tetrahydro-6-phenyl-imidazo(2,1-b)thiazole hydrochloride,

* Levacide, * Levadin, * Levamisole hydrochloride [USAN 1993],

* Levamisole hydrochloride [USAN], * Meglum, * Nemicide, * Nilverm forte,

* Niratic hydrochloride, * Niratic-puron hydrochloride, * NSC-177023,
* R 12,564, * R 12564, * R-12,564, * Ripercol-L, * Solaskil, * Spartakon,

* Stimamizol hydrochloride, * Tramisol, * Tramisole, * Worm-chek,

Chemical Name:

(-) - (S) - 2, 3, 5, 6 – tetrahydro – 6 – phenylimidazo [2,1-b] thiazole monohydrochloride

Molecular Formula:

C₁₁H₁₂N₂S.HCl

Molecular Weight :

204.29+36.46=240.75

CAS No. :

16595-80-5

Chemical Structure:

Specification:

EP/USP/CP

Pharmacodynamic
Properties:

Levamisole refers to Levo tetramisole, it is the Levo Isomer of tetramisole. It can selectively inhibit succinate dehydrogenase in parasite’s muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite’s muscle metabolism lacks of oxygen and leads to decreasing of energy.
L-isomer is active against helminthes with 1-2 times higher active efficiency and lower toxic and side effects than tetramisole. It is a broad spectrum anthelmintic with a very good activity against roundworms, hookworms, whipworms, and strongyloises stercoralis. It is an immunomodulator and has effect on rheumatic disorders.
Levamisole is also a good alternative in cases of benzimidazole resistance.

Storage:

Keep container tightly closed in a cool, well-ventilated area.

MSDS:

Provide as per request after the order or contract is signed.