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| Synonyms: |
* ((2-((Methoxyacetyl)amino)-4-(phenylthio)phenyl)carbonimidoyl)bis(carbamic acid), dimethyl ester,
* CARBAMIC ACID, ((2-((METHOXYACETYL)AMINO)-4-(PHENYLTHIO)PHENYL)CARBONIMIDOYL)BIS,
* Carbamic acid, ((2-((methoxyacetyl)amino)-4-(phenylthio)phenyl)carbonimidoyl)bis-, dimethyl ester,
* Dimethyl ((2-(2-methoxyacetamido)-4-(phenylthio)phenyl)imidocarbonyl)dicarbamate,
* EINECS 261-205-0,
* Febantel [USAN:BAN:INN],
* Febantelum [INN-Latin],
* N-(2-(2,3-Bis-(methoxycarbonyl)-guanidino)-5-(phenylthio)-phenyl)-2-methoxyacetamide,
* Negabot Plus Paste,
* Oratel,
* Rintal,
* DrontalPlus
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| Chemical Name: |
Dimethyl [[2-[(methoxyacetyl)amino]-4-(phenylthio)phenyl]carbonimidoyl] biscarbamate |
| Molecular Formula: |
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| Molecular Weight : |
446.48 |
| CAS No. : |
58306-30-2 |
| Chemical Structure: |
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| Specification: |
EP |
Pharmacodynamic
Properties: |
The mechanism of Febantel action is primarily based on interference with the carbohydrate metabolism of the worm. The suppression of mitochondrial reactions (inhibition of fumarate reductase) and interferencewith glucose transport act not only on all developmental stages of the helminths but also on the eggs containing the larvae. Benzimidazoles bind to the structural protein tubulin, thereby preventing its polymerization to microtubules which provide the transport system for the absorbing cells. The consequence of blocking this transport activity is incomplete absorption and digestion of nutrient particles and cellular autolysis through activation of lysosomal enzymes.
Febantel is a broad-spectrum anthelmintic, it is active against nematode parasites including whipworms.
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| Storage: |
Keep container tightly closed in a cool, well-ventilated area |
| MSDS: |
Provide as per request after the order or contract is signed. |
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