DMSO has solubility and permeability for many drugs, and diminishes inflammation and acesodyne and accelerates blood circulation and wound healing. It is reported internationally that all-round testing and pathology dissection implemented by Shenyang College of Pharmacy, Beijing Research Institute of Pharmacy, Chinese Drug Testing Center, etc in 1950s proved that half lethal dose of DMSO in China was 22.4±1.4 g/kg, and almost the same to international document report and belonged to innocuity. 160 medical treatment institutions including Beijing Union Medical College Hospital took clinic probation in 1950s and set up special clinic in Benxi city, and accumulated many data. Practice proves that it has curative effect for psoriasis, arthritis, bursitis, folliculitis, rheumatoid, tympanitis, coryza, appendagitis, toothache, hemorrhoids, strain, strain of lumbar muscles, burn, trauma, etc. It is widely used in Topsyne unguent, dermatophytosis drug and other drugs for exterior use, external preparations in many hospitals.