Bicalutamide

General name: bicalutamide

Chemical structure:

Chemical name: （±）-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4- fluorophenyl) sulfonyl]-2-hydroxy-2-methylpropanamide

CAS No: 90357-06-5

Formula: C₁₈H₁₄F₄N₂O₄S

Molecular weight: 430.37

Use: antineoplastic; anti-androgen

Intermediates for bicalutamide

1)      4-amino-2-(trifluoromethyl)benzonitrile

2)      N-[4-cyano-3-(trifluoromethyl)phenyl]methacrylamide

3) N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide

4)N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-

methylpropanamide

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