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 nutrition ingredients--Thiamine HCL (Vitamine B1 HCL)

Introduction:Thiamine Hydrochloride: Hydrochloride salt form of thiamine or vitamin B1; occurs as white, hygroscopic crystals or crystalline power that usually has a slight characteristic odor.Freely soluble in water, insoluble in ether, decomposes at 247 C; the form in which thiamine is generally employed for the prophylaxis and treatment of thiamine deficiency states orally and intramuscularly.
Appearance: White crystalline powder
Molecular formula: C12H18Cl2N4OS
Molecular weight: 337.27
Solubility: H2O: 0.1 g/mL at 20°C, clear, colorless
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong reducing agents.
CAS Number:67-03-8
Assay:98.0%~102.0%
Application: Thiamine hydrochloride is effective for the treatment of thiamine deficiency or beriberi whether of the dry (major symptoms related to the nervous systom) or wet (major symptoms related to the cardiovascular system)variety.Thiamine hydrochloride should be used where rapid restoration of thiamine is necessary,as in Wernicks encephalopathy,infantile beriberi with acute collapse,cardiovascular diease due to thiamine deficiency,or neuritis of pregnancy if vomiting is severe.It is also indicated when giving IV dextrose to individuals with marginal thiamine status to avoid precipitation of heart failure.

Specification: USP27

Test Item

Specification

Identification

A: Infrared Absorption

B: A solution responds to the tests for Chloride

Water

≤ 5.0 %

pH

2.7~3.4

Residue on Ignition

≤0.2%

Absorbance of Solution

≤0.025 (at 400nm)

Nitrate

No brown ring is produced at the junction of the two layers.

Organic Volatile Impurities

Meets the requirements.

Chromatographic Purity

The total of the responses of all secondary peaks is not greater than 1.0% of the total of the responses of all of the peaks.

Assay

98.0%~102.0%



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