Oxyresveratrol

CAS: 29700-22-9
Structural Formula:

Mainly reguarding 3, 5-dihydroxybenzoic as starting material,obtained through Methylation, restore , chlorinated, Wittig Horner reaction , or obtained through further demethylating, with haloacetic acids (or halogenated acetate)reacting in alkali action.This method is Preparation easy and reproducibility good. These compounds or medicinal salts can inhibit microglia activation, which can be used for the treatment of Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis and other neurodegenerative diseases.  R1 and R2 are H, methyl, ethyl and propyl, CH2COOH, CH2COOR (R-methyl, ethyl and propyl, alkyl); Ar contains various substituted benzene, aromatic heterocyclic base (such as pyridine, quinoline-based, furan-based, the terthiophene base, pyrrole base, etc.).

For example