Products
PYRIMETHANIL
Fungicide
FRAC 9; anilinopyrimidine
NOMENCLATURE
Common name pyrimethanil (BSI, draft ISO)
IUPAC name N-(4,6-dimethylpyrimidin-2-yl)aniline
Chemical Abstracts name 4,6-dimethyl-N-phenyl-2-pyrimidinamine
CAS RN [53112-28-0] Development
codes SN 100309 (Schering); ZK 100309
PHYSICAL CHEMISTRY
Mol. wt. 199.3 M.f. C12H13N3 Form Colourless
crystals. M.p. 96.3 ºC V.p.
2.2 mPa (25 ºC) (OECD 104) KOW logP
= 2.84 (pH 6.1, 25 ºC) Henry 3.6 ´ 10-3 Pa
m3 mol-1 (calc.) S.g./density 1.15
(20 ºC) Solubility In water 0.121 g/l (pH
6.1, 25 ºC). In acetone 389, ethyl acetate 617, methanol 176,
methylene chloride 1000, n-hexane 23.7, toluene 412 (all in
g/l, 20 °C). Stability Stable in
water within the relevant pH range. Stable for 14 d at 54 ºC. pKa 3.52,
weak base (20 °C) (OECD 112)
COMMERCIALISATION
History Reported by G. L. Neumann et al. (Proc.
Br. Crop Prot. Conf. - Pests Dis., 1992, 1, 395).
Introduced by Schering (now Aventis CropScience). Manufacturers Aventis
APPLICATIONS
Biochemistry Inhibitor of methionine biosynthesis
leading to inhibition of the secretion of enzymes necessary for infection. Mode
of action Protectant (in Botrytis) and both protective
and curative action (in Venturia). Uses Control
of grey mould (Botrytis cinerea) on vines, fruit, vegetables
and ornamentals. Control of leaf scab (Venturia inaequalis or V.
pirina) on pome fruit. Phytotoxicity May
be phytotoxic in closed systems at ³80% r.h. on certain species. Formulation
types SC.