General Name : Timulin Hydrogen Fumarate
Molecular Formular: C₂₈H₄₇NO₄S.C₄H₄O₄
Specification:
A) Timulin Hydrogen Fumarate Pure
B) Timulin Hydrogen Fumarate 80%

Technical Specifications	A(PURE)	(B) 80%
Appearance	White crystal powder	Creamy White granules
Identification	IR-spectrum
PH-Acidity	From3.1 to 4.1	From3.1 to 4.1
Loss on drying (%)	Not more than 0.5	Not more than 3
Heavy Metals (ppm)	Not more than 10
Fumaric acid assay (%)	18.6-19.4
Assay (HPLC)	BET.98.0-102.0% D.B.	BET.780-820mcg/mg D.B.

Indication and dosage:
Tiamulin is a semi-synthetic derivative of pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and highly active against mycoplasmas and serpulina (Treponema) hyodysenteriae. The range of values of Minimal Inhibitory Concentrations (MICs) against streptococci and staphylococci is between 0.015 and 0.15ug/ml, with a few exceptions among streptococcus faecalis strains.
Tiamulin is indicated for swine dysentery, swine enzotic pneumonia and chronic respiratory disease in poultry. Tiamulin is also useful in the prevention and treatment of pleuropneumonia caused by Actinobacillus pleuropneumoniae(APP). At low doses ,tiamulin is an effective performance enchancer.The most efficient biological activity of Tiamulin is evident in the area of mycoplasmas control, surpassing such antibiotics as Tetracycline HCL and Tylosin tartrate which are widely used for the treatment of infections. The MIC values of Tiamulin against strains of mycoplasmas range from 0.004 to 6.25ug/ml. Tiamulin acts bacteriostatically.

For the metaphylaxis of swine dysentery and enzootic pneumonia complex,fowl chronic respiratory disease and improvement in growth and feed efficiency, an inclusion rate of 25-30 ppm tiamulin fumarate in the diet is recommended. If for tratment of wine dysentery and enzootic pneumonia complex, fowl chronic respiratory disease, an inclusion rate of 120-200 ppm tiamulin fumarate in the diet is recommended.

Caution: Don't use together with Monesin, Salinomycin. Don't touch eyes and skin.
Storage: Keep in dry, cool areas ,protected from direct sunlight ; sealed after use.
Shelf Life: Two years