Chemical name:
Tilmicosin(IUPAC): (10E,12E)-(3R,4S,5S,6R,8R,14R,15R)-14-(6-deoxy-2,3-di-O-methyl-b-d-allo-hexopyranosyoxymethyl)-5-(3,6-dideoxy-3-dimethylamino-b-d-gluco-hexapyranosyloxy)-6-[2-(cis-3,5-dimethyl-piperidino)ethyl]-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide
C.A.S. number: 108050-54-0
Synonyms: 20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin
Structural formula :

Molecular formula: C₄₆H₈₀N₂O₁₃
Molecular weight: 869.15
Melting point: Not determined
Standard: USP28
Description:
A white or off-white powder, Freely soluble (1500 mg/L or greater) in organic solvents (hexane,acetone, acetonitrile, chloroform, dichloromethane, ethyl acetate, methanol, tetrahydrofuran); water solubility is temperature and pH dependent, but is 566 mg/mL at pH 7 and 25°C.
Purity:
Tilmicosin consists of 82-88% cis isomer and 12-18% trans isomer, as determined by liquid chromatographic assay.(85%MIN)

Indications:
Tilmicosin is a macrolide antibiotic synthesized from tylosin,It developed for veterinary use only.and it has an antibacterial spectrum similar to tylosin with enhanced activity against Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. It is recommended for treatment and prevention of pneumonia in cattle, sheep,poultry and pigs, Not show resistance and cross-resistance with other antibiotic often used in clinic. Mainly used in the Pleuropneumonia and the infection caused by Pasteurellaceae , Pasteurella and mycoplasma

Dosage:
Formulations of tilmicosin include an injectable for use in cattle and sheep (30% Injection) and premix formulations for swine (4%, 10% & 20% Premix). The recommended dose of the injectable formulation in both cattle and sheep is a single subcutaneous (SC) injection of 10 mg/kg BW. Recommended dose for swine in feed is 200-400 mg/kg of feed for 10 to 21 days, equivalent to 8-20 mg/kg BW per day.

Packing:
5kg/drum 10kg/drum 20kg/drum
Storage:
Protected from light , stored hermetically and in a dry place.
Shelf Life:
Three years