L-Citrulline Series |
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For most of us, we heard about Nitric Oxide and it's function in our body from the famous new drug discovery called Viagra, produced by Pfeitzer. This is a drug that has been designed to work on erectile dysfunction in men by helping to increase blood circulation to the penis. One of the substances that are required for blood vessels to dilate in the body and allow more blood to flow is called Nitric Oxide(NO). Nitric oxide (NO)is an inorganic gas synthesized by enzyme nitric oxide synthase(NOS) in which amino acid L-Arginine is oxidized to NO and equal amount of L-Citrulline, which is the only way to manufacture NO in our body. When nitric oxide is formed through an enzymatic reaction in the body, an even more useful amino acid is formed: L-Citrulline. The body can recycle L-Citrulline back into L-arginine, which can then be converted back into nitric oxide--and more NO is yes for the body. Though L-Citrulline is an amino acid, it is not found in the proteins we consume, but it is produced in notable amounts by the liver and intestines from other amino acids. Now, scientists think that L-citrulline itself may serve as a blood vessel/pressure regulator, and an even more efficient modulator than L-arginine. A study on rats found that L-citrulline—by recycling back into L-arginine—produced substantial relaxation of blood vessels and increased the production of nitric oxide. Besides nitric oxide, the body also requires ample amounts of a chemical called cyclic GMP, which causes relaxation of smooth muscles in penile vessels, leading to erection. The longer cyclic GMP is allowed to persist, the greater the chance for increased blood flow to the penis, thereby generating an erection. In experiments cited by doctors from the Department of Pharmacology, School of Medicine, Complutense University, Madrid, Spain, L-Citrulline was shown to double intracellular cyclic GMP levels. Sexual health Citrulline is an amino acid that supports the body in optimizing blood flow throught its conversion to L-arginine in the endothelial cells and then nitric oxide. It is considered to be the patented nutrient and a new unique, natural way to improve libido and sexual vitality, which promotes better circulation thus enhancing libido. Support of healthy sexual function is completely safe and without known side effects. Now widely used by men in lieu of medically prescribed potency drugs to support the body's production of nitric oxide. Improving Performance Some Scientific Reprots show that L-Citrulline bonded to malate that has been shown to reduce lactic acid build up and assist in eliminating toxic ammonial levels that can severly impair performance. Another demonstrations also show Citrulline as having a protective effect against acidosis and ammonia poisoning. The metabolic actions of Citrulline clearly explain the anti-fatigue properties in man and shows great promise to its uses as a performance enhancer for athletes. Compare with L-Arginine. L-Citrulline maybe more potent than L-arginine because the body's production of nitric oxide can be impaired, due to interference by other chemicals .But citrulline overcomes impaired nitric oxide synthesis even batter than L-arginine In the meantime, research has suggested that L-citrulline may be a more efficient way to get more L-arginine to the body, even better than consuming it directly, since dietary L-arginine is not readily absorbed. L-citrulline is credited not only with enhancing blood flow, but also for improving erectile function and reducing symptoms of sickle cell anemia. Systematic evaluations of this theory will soon begin. L-Citrulline
L-Citrulline DL-Malate 1:1 Molecular Formula: C10H19N3O8 CAS(法定编号): 54940-97-5
L-Citrulline DL-Malate 2:1 Molecular Formula: C16H32N6O11
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