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Drug Catalogue
List of Products
Other names: Hesperetin-7-rhamnoglucoside, Cirmtin, Hesperetin-7-rutinoside Chem. name: 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy- Structure:
M.F. & M.W.: C28H34O15; 610.55 Physical properties: crystal in the shape of tree branches (precipitation
under pH6-7); M.P.: 258-262 Plant source: Galium mollugo Linn., above ground part[1]; fruit of Citrus medica L. var. sarcodactylis (Noot.) Swingle[2], C.tankan Hayata[3], Poncirus trifoliata(L.) Raf.[4], and Citrus limon Burm.[5]; C. limonia Osbeck., skin of the fruit; C. medica L., mature fruit[5]; Capsella bursa-pastoris(L.) Medic, whole plant including root[7]. Function and Applications: 1. Enhance the action of Vitamin C [8]: relief the blood cell coaggualtion in conjunctiva of guinea pig due to lack of Vitamin C; it is also reported that it can reduce blood cell coaggualtion in horse. The life span of rats is prolonged [9] when the product is fed with thrombogenic feed or feed that may cause atherosis. Can raise the Vitamin C concentration in adrenal gland, spleen and white blood cell in guinea pig.[10] 2. Anti-viral capability: when fibrocytes of mice are treated with the
product in 200 3. Other: prevent injury from cold[12]; inhibit
aldehyde reductase in lens of rat eyes[13].
Other Names: Rutoside, Vitamin P, Violaquereitrin Chemical Name: 4H-1-Benzopyran-4-one,3-[(6-O-(6-deoxy- Molec. struct.:
M.F. & M.W.: C27H30O16; 610.51 Physical properties: light yellow needle like crystal (in water); M.P.:
176-8 Plant source: Ruta graveolens L., plant oil[2]; Scphora japonica L., main part of fruit[3,4]; Hypericum aseyron L., full plant; Berchemia polyphylla Wall, var leioclada Hand. -Mazz.[5]; Mallotus japonicus Muell.-Arg, leaf[6]; Fagopyrum esculentum Moench seed. Function and Application: 1. Anti-inflammatory action: apparent suppression of inflammation due to planted wool when the product is injected into abdominal cavity[8]. Sodium rutin sulfate has very strong anti-inflammatory action to edema in rat[9]. 2. Vitamin P like action: maintain the strength of blood vessel, reduce its permeability and brittleness; degreasing action to liver soaked in fat, esp. when used with glutathione. 3. Antiviral action: best suppression to phlyctenular stomatitis virus
at product concentration of 200 4. Inhibition of aldehyde reductase: 95% inhibition at a concentration of 10^-5M [12], which facilitates the treatment of diabetic cataract. 5. Toxicity: mice, intravenous injection, LD50: 950mg/kg. 6. Clinic use: ofr the prevention of intracerebral hemorrhage, hypertension, retinal hemorrhage, purpura and acute hemorrhagic nephrosonephritis; for treatment of chronic tracheitis with effective rate at 84.8% and 98%. Its derivative, troxerutin, or Venoruton, is applied clinically for burn, arthritis, and all kinds of blood vessel diseases. Commodity drug is available abroad[14], while the drug has been successfully developed in the nation. Effective rate for cerebrovascular diseases is 87.8%; 88% for retinal edema and hemorrhage[3].
Other Name: L-Dopa Chemical Name: L-Tyrosine, 3-hydroxy- Molec. Struct.:
M.F. & M.W.: C9H11NO4; 197.19 Physical properties: clear to white odorless and tasteless crystal or
crystalline powder; needle like crystal (in water; M.P.: 276-278 Plant Source: Vicia faba L.; Mucuna cochin-chinensis(Lour) A.Cheval., seed[3]; M.semporvirens Hemsl., seed[4]; M.birdwoodiana Tuteh., seed[5]; Stizolobium caprtatum (Sweet) O.Kuntze. Funtions and Applications: One of the precursors for in vivo synthesis of noradrenalin and dopamine, it can raise the level of dopamine in brain tissue. As Parkinson's disease is caused by deficiency of dopamine in brain, it is used clinically for the treatment of the disease. It can ease the symptom (exogenous dopamine cannot overcome blood-brain barrier to be effective); also effective to similar simptom caused by Mn or Co poisoning[6]; some therapeutical effect to hepatic coma caused by acute hepatic failure. Toxicity: oral LD50 (mg/kg): mice 3650, rats >40000, rabbit 609.
Other Name: Meletin, Sophretin. Chem. Name: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy- Structure:
M.F. & M.W.: C15H10O7, 302.23 Physical Property: yellow needle like crystal (dihydrate in dilute ethanol);
dehydrate at 95-97 Plant Source: Quercus iberica, skin and leaves[4]; Dysosma veitehii(Hemsl.et Vils.) Fu[5]; Hypericum ascyron L., full plant[6]; Apocynum lancifolium Rus., leaves[7]. Functions and applications: fairly good expectorant and antitussive; some antiasthmatic effect; lowering of blood pressure, reducing the brittalness of capillary vessel, lowering blood lipid, dilation of coronary artery, increasing the flow in coronary artery. For the treatment of chronical bronchitis, accessory treatment of coronary heart diseases and hypertension[8-10]. Toxicity: oral dose, mice: LD50 at 160mg/kg[1].
Other Names: Artemisinin, Qinghaosu Chem. Name: 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one,
octahydro-3,6,9-trimethyl-, [3R-(3 Molec. Struct.:
M.F. & M.W.: C15H22O5; 282.14 Physical properties: clear needle-like crystal; M.P.: 156-157 Plant Source: Artemisia annua L., leaves[1-4]. Functions and Applications: According to over 2000 clinical case studies, when used for the treatment of tertian fever, it is better than chloroquine in terms of time to suppress the pathogen. No adverse effect in clinical cases. Esp. useful for the treatment of cases resistant to chloroquine. However, the short term recurrance rate is higher than chloroquine. Dosage: according to large amount of clinical study, for the treatment of malaria, use intramuscular injections of 0.3g each time each day for three days, for a total amount of 0.9-1.2g; double first dose for severe case.
Chem. Name: Molec. Struct.:
M.F. & M.W.: C21H18O11; 446.35 Physical Properties: yellow crystal; M.P.: 223 Fuctions and Applications: 1. anti-imflammation & anti-hypersensitivity: in guinea pig, relief from hypersensitive constriction of isolated trachea, and hypersensitive asthma of the animal [7-10]; synergetic effect with ephedrine[9]; slight anti-histamine effect; suppression to PSA, PCA and skin reaction caused by histamine[11]; suppression to hypersensitive edema and infection[12, 13]; lower the permeability of capillary vessel in mice ears [14]; prevention of pneumonemia in mice due to low atmospheric pressure[15]. 2. anti-bacterial effect: 3% eyedrop can be use to treat trachoma with similar effect to rifampin[16]. 3. diuretics: diuretic to rabbit[17]. 4. cholagogue: increase bile excretion in dog and rabbit[18]. 5. antipyretic: antipyretic to rabbit with sympton caused by vaccine or yeast (abdominal or intravenous injection)[19]. 6. depressor: applied through intravenous injection, hypodermic injection, anaesthesia for dog, cat and rabbit[18]. 7. sedative: inhibit the spontaneous activities of mice 8. other: reduce the death rate of mice due to strychnine poisoning;
2-5 times of LD50 increase with 10 9. clinic use: mainly for the treatment of hepatitis in the nation, with pronounced therapeutical effect[22].
Other Names: 3-Caffeoylquinic acid, Caffeotamic acid Chemical Name: Cyclohexanecarboxylic acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxy-2-propenyl]oxy]-1,4,5-trihydroxy-1,
[1S-(1 Structure:
M.F. & M.W.: C16H18O9: 354.30 Physical Properties: needle shaped crystal (semi-hydrate in water). dehydration
at 110 Functions and Applications: broad anti-bacteria effect, but quenched
by proteins in the body[11]. When administrated through oral
dose or abdominal injection, similar to caffeic acid, it can enhance the
central excitation of rats, peristalsis of small intestine of rats and
mice, and uterine tension in rats. It can also enhance the bile excretion
in rates Very low toxicity, infant mice, oral LD50 > 1g/kg, abdominal injection > 0.25g/kg[23]
S.F.:
M.F.:C45H74O Function: It is one of important intermediate which can be synthesized coenzyme Q10 and vitamin K2
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90%, 92%, 95%,
98%
-L-mannopyranosyl)-
-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methyoxyphenyl)-,(S)-
(softening point at 250
g/ml solution, the cells can resist the attack from phlyctenular
stomatitis virus for 24 hours. HeLa cells treated with the product can
resist the infection from flu virus. The antiviral activity of the product
may be attenuated by hyaluronidase [11]
CH3OHmax
nm: 258.361; IR
KBrmax cm-1: 3400(OH),
1670(C=O), 1620, 1520, 1470(C6H5-)[1]. 
): 220.5(3.97), 280(3.42)[1];
IR
:
146.9(C2), 135.8(C3), 175.9(C4), 156.2(C5), 98.3(C6), 164.0(C7), 93.5(C8),
160.8(C9), 103.1(C10), 122.1(C1'), 115.2(C2'), 145.1(C3'), 147.7(C4'),
115.7(C5'), 120.1(C6') [2,3]
