Basic info.
Alias:4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Molecular structure:
Molecular formula:C22H20N2O5
Molecular weight:392.40
CAS RN:86639-52-3
Quality standard
| 7-Ethyl-10-hydroxycamptothecin Quality standard |
Inspection item |
Standard value |
Result |
Appearance |
light yellow white crystalline powder |
slight yellow to white crystalline powder |
Melting point |
215～ 216℃ |
215℃ |
Identification |
(1)in accordance with ultraviolet absorption;
(2)in accordance with infrared absorption spectrum |
qualified |
Assay test |
HPLC(area normalization) |
7-Ethyl-10-hydroxycamptothecin |
≥ 98.0 % |
99.2% |
Total impurities |
≤2.0% |
≤1.0% |
(S)-10-Hydroxycamptothecin |
≤0.3% |
qualified |
7-ethylcamptothecin |
≤2.0% |
≤1.0% |
Unknown impurity |
≤0.5% |
Na |
Loss on dry |
≤1.0 % |
qualified |
Heavy metals |
≤10ppm |
qualified |
Residue on ignition |
≤0.1 % |
qualified |
Clarity and color of solution |
clear transparent |
qualified |
|
