Aldehydes chemicals Products
Vanillin FCC IV
Ethyl vanillin
4-Hydroxybenzaldehyde/P-Hydroxybenzaldehyde
Methanedisulfonic Acid series Products
Methanedisulfonic Acid
Methanedisulfonic acid, disodium salt
Methanedisulfonic acid, dipotassium Salt
1,5,2,4-Dioxadithiane 2,2,4,4-tetraoxide (MMDS)
API and Pharmaceutical Intermediates
LCZ696
Huperzine A
Phentolamine Mesylate
Suplatast Tosilate
2-Methoxyethylamine
1-Boc-3-azetidinone
2,3-O-isopropylidene-D-glyceraldehyde
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Pharmaceutical & Agrochemical Intermediates
2,4-Pyridinedicarboxylic acid
(S,S)-2,8-Diazabicyclo[4,3,0]nonane
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
N,N'-Dimethylpiperazine / 1,4-dimethylpiperazine
4-Hydroxyphenethyl alcohol
3,5-Di-tert-butyl-4-hydroxybenzaldehyde
Products
LCZ696
[Chemical Name]: | Valsartan/sacubitril; LCZ-696; LCZ 696 |
[Synonyms ]: | Entresto; L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, compd. with α-ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoate, sodium salt, hydrate (2:2:6:5); trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3-methyl-2-(pentanoyl{2”-(tetrazol-5-ylate)biphenyl-4-ylmethyl}amino)butyrate] hemipentahydrate; trisodium 3-((1S,3R)-1-(biphenyl-4-ylmethyl)-3-(ethoxycarbonyl)butylcarbamoyl)propionate (S)-3-methyl-2-(pentanoyl-(2-(tetrazol-1-at-5-yl)biphenyl-4'-ylmethyl)amino)butyrate hemipentahydrate |
[CAS No.]: | 936623-90-4 |
[Structure Formula]: | |
[Molecular Formula]: | C48H55N6Na3O8 / C48H55N6O8(-3) |
[Molecular Weight]: | 843.99 |
[Solubility]: | in DMSO > 10 mM |
[Purity ( Assay ) ]: | 99.0% min |
[Biological activity ]: | LCZ696 is a first-in-class dual inhibitor of the angiotensin II receptor(AT II receptor) and neprilysin; a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). |
[Usage/Application]: | LCZ696 is used for the treatment of heart failure , LCZ696 is believed to be able to reduce the pressure of heart failure, and promote heart muscle ability |
[Packing]: | In small aluminum foil bag or 1kg-10kg Tin |